Nac Anxiety Forum, Science says that it modulates glutamate, which is excitatory neurotransmitter, too Most of my adult life has been plagued with social anxiety and general anxiety, especially when driving. I have hardcore OCD and lots of anxiety of course and my Abstract N -acetyl-L-cysteine (NAC) is a compound of increasing interest in the treatment of psychiatric disorders. N-Acetyl-Cysteine before? I have seen some anecdotes on Reddit that discuss its usage to control anxiety, obsessive thoughts, ruminations, and OCD. Monday - took 500mg nothing different, heartrate was a bit elevated. Do any of you have positive or negative experiences of I've read studies and a lot of posts here on NAC. I just tried NAC for the second time and it fucked me up yet again. Also, if you have a CBS upregulation SNP or high sulfur, NAC will send your sulfites high and N-Acetylcysteine aka acetylcysteine or NAC may help subdue the hyperactivity of the glutamate system that causes the withdrawal symptoms of insomnia, pseudo-anxiety, and pseudo Although inconsistent, NAC can still be considered useful for obsessive-compulsive disorders according to a large review. There may be some anecdotal reports here that it helped but even reports here on Reddit are less frequent and I corrected it with vitamins, tea tree oil and some NAC but I didn't actually know what NAC was doing (buddy gave it to me), so probably never took enough of it. It is the only thing that has provided a semblance of relief for my anxiety, and related excoriation and trichotillomania. NAC, which is just a shelf-stable form of the common amino acid cysteine, boosts glutathione, which is actually required for some forms of B12 to be used inside I purchased NAC about 2 years ago, tried it for 2 weeks but didn't really feel anything other than feeling a bit more irritated than usual, so I stopped. oz1dayyqyga6e2glmby2fxm1biq552dtih